Home  >  Products  >  14-3-3, 30, 33kD (Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein, Polypeptide, 14-3-3 epsilon, Mitochondrial Import Stimulation Factor L, Protein Kinase C Inhibitor Protein 1, YWHAE)

14-3-3, 30, 33kD (Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein, Polypeptide, 14-3-3 epsilon, Mitochondrial Import Stimulation Factor L, Protein Kinase C Inhibitor Protein 1, YWHAE)

Cat no: 0014-04D


Supplier: United States Biological
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Mammals express seven distinct 14-3-3 isoforms (gamma, epsilon, beta, zeta, sigma, theta, tau) that form multiple homo- and hetero- dimers, thus rendering 14-3-3 as a key multifunctional regulatory molecule. 14-3-3 isomers have been implicated in several neurological disorders: for example isoforms gamma, epsilon and beta are expressed in the cerebrospinal fluid of Creutzfeldt-Jakob patients, but not patients suffering from other neurological conditions such as Alzheimer's. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:500 Optimal dilutions to be determined by the researcher. Positive Control: Jurkat cell lysates. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: 0014-04D
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ul
Form: Supplied as a liquid. No preservative added.
P type: Pab
Isotype: IgG
Purity: Serum
Additional info: Recognizes human 14-3-3 proteins. Species Crossreactivity: mouse, rat.

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