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14-3-3, gamma (Protein kinase C inhibitor protein 1, KCIP-1, Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide, YWHAG)

14-3-3, gamma (Protein kinase C inhibitor protein 1, KCIP-1, Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide, YWHAG)

Cat no: 0014-07E

Supplier: United States Biological
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14-3-3 proteins are present as multigene Protein kinase C inhibitor protein 1, KCIP-1 families in most organisms. Signal-induced phosphorylation has the ability to change protein function. Sometimes, however, phosphorylation is not enough to change a protein's function. 14-3-3 proteins play an important role of bringing signal transduction to completion. They regulate many cellular processes that are important in cancer biology, such as apoptosis and cell-cycle checkpoints. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1,000. Detects a band of ~ 33kD. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: 0014-07E
Reactivities: Human
Hosts: Mouse
Applications: Western Blot
Size: 100ul
Form: As reported
P type: Mab
Isotype: IgG1,k
Purity: Ascites
Alternative names: Protein kinase C inhibitor protein 1, KCIP-1, Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide, YWHAG
References: 1. Hu, X., Addlagatta, A., Lu, J., Matthews, B. W., and Liu, J. O. (2006) Elucidation of the function of type 1 human methionine aminopeptidase during cell cycle progression, 103, 18148-18153.
Additional info: Specific for human 14-3-3 gamma. Species Crossreactivity: Reacts with the human form of intact, non-modified N-terminus 14-3-3 gamma. The naturally occurring form of 14-3-3 gamma in which the N-terminus Met is removed and the Val is acetylated is not recognized by this antibody.

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