2-Methoxyestradiol (2-ME) is major estradiol metabolite that acts as a potent inhibitor of endothelial cell proliferation and angiogenesis. It displays little affinity for classical estrogen receptors.
Solubility:
~10mg/ml (DMSO), ~10mg/ml (EtOH)
Molecular Weight:
~302.41
Storage and Stability:
Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.