Diindolylmethane (DIM) is a natural compound present in food plants of the Brassica genus, including broccoli, cabbage, Brussels sprouts, cauliflower and kale. Displays antitumor and proapoptotic properties in animal and in in vitro models of cancer. Also acts a selective and potent inhibitor of cancer stem cells, and HDAC activity in prostate cancer cells. Recently, it has been shown that DIM induces apoptosis in ovarian cancer cells by inhibiting JAK2/STAT3.
Solubility:
DMSO (25mg/ml)
Molecular Weight:
~246.31D
Storage and stability:
May be stored at RT for short-term only. Long-term storage is recommended at -20 degrees C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
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