A Cyclase IX (P974) Peptide

Cat no: BS9246P

Supplier: Bioworld Technology, Inc.

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Classically, adenylyl cyclases respond to receptor-initiated signals, mediated by the Gs and Gi heterotrimeric G proteins. The binding of an agonist to a Gs-coupled receptor (i.e., alpha beta-adrenergic receptor) catalyzes the exchange of GDP (bound to Galpha s) for GTP, dissociation of GTP-Galpha s from Gbg and Galpha s-mediated activation of adenylyl cyclase. The most abundant cerebral adenylyl cyclases appears to be adenylyl cyclase IX. AC IX is confined to the gray matter and its expression is mainly neuronal, with its highest expression located at the hippocampus. ACIX is also expressed in heart, pancreas and thyrocytes. AC I and AC IX are regulated reciprocally by intracellular free Ca2+. The inhibition of AC IX by Ca2+ is blocked by the calcineurin inhibitors FK506 and cyclosporin A.

Catalogue number:	BS9246P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	O60503
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide A Cyclase IX (P974). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	ADCY 9; Adenylate cyclase 9; Adenylate cyclase type 9; Adenylate cyclase type IX; Adenylyl cyclase 9; ATP pyrophosphate lyase 9; KIAA0520; Type IX adenylyl cyclase; Type IX ATP pyrophosphate lyase
Additional info:	This peptide can be used with studies using BS9246 A Cyclase IX (P974) pAb.

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A Cyclase IX (P974) Peptide

Cat no: BS9246P

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