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a1-Acid Glycoprotein (Orosomucoid)

Cat no: A0550-09B


Supplier: United States Biological
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Alpha 1 Acid Glycoprotein (AGP) is an acute phase plasma protein synthesized by the liver. The protein is believed to regulate the interaction between blood cells and endothelial cells, and together with haptoglobin and C reactive protein, also regulates the extravasation of the cells during infection and inflammation. AGP is a major acute phase reactant, both in human and in rat. In human plasma, AGP (44kD) is found at levels of 0.5-1.4 mg/ml. Its concentration in blood plasma is elevated during acute inflammation, such as trauma, malignancies, myocardial infarction, rheumatoid arthritis, bacterial infections, after major surgery, in cases of chronic pain etc, and can be used for the diagnosis of inflammatory conditions. Cellular Localization: Secreted Positive Control: E Coli-derived fusion protein. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: A0550-09B
Reactivities: Human
Hosts: Chicken/Bird
Applications: Western Blot
Size: 50ug
Form: Supplied as a liquid in PBS, pH 7.2.
P type: Pab
Isotype: IgY
Purity: Purified by immunoaffinity chromatography.
References: Prowse KR & Baumann H Molecular characterization and acute phase expression of the multiple Mus caroli alpha 1-acid glycoprotein (AGP) genes. Differences in glucocorticoid stimulation and regulatory elements between the rat and mouse AGP genes. J Biol Chem 265:10201-9 (1990).
Additional info: Species Crossreactivity: Crossreacts with Human. Not yet tested in other species.

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