Alpha-1-acid glycoprotein (orosomucin) (A1AG) is a major serum glycoprotein of unknown physiological function. (1)alpha-1-acid glycoprotein (A1AG) has been implicated in cellular inflammation by increasing tissue factor expression and tumor necrosis factor alpha secretion of monocytes. alpha-1-acid glycoprotein (A1AG) protein is associated with five asparaginyl-linked complex oligosaccaride chains, the proportions and identities of which are altered in several physiological and pathological conditions (2)alpha-1-acid glycoprotein (A1AG) is also clinically important as a non-specific drug binder in serum.
Applications:
Suitable for use in ELISA. Other applications not tested.
Recommended Dilution:
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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