Home  >  Products  >  A77 1726, (N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide, 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide)
A77 1726, (N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide, 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide)

A77 1726, (N-(4-Trifluoromethylphenyl)-2-cyano-3-hydroxycrotonamide, 2-Cyano-3-hydroxy-N-[4-(trifluoromethyl)phenyl]-2-butenamide)

Cat no: 167739

Supplier: United States Biological
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Physiologically active metabolite of the immunosuppressive drug leflunomide. Inhibits the activity of dihydrorotate dehydrogenase and of protein tyrosine kinases. Blocks TNF-mediated NF-kB activation in a dose- and time-dependent manner. Also inhibits the activity of COX-2 in vitro and in vivo. Solubility: DMSO Molecular Weight: ~270.21D Storage and Stability: Store at -20 degrees C. Protect from light.
Catalogue number: 167739
Size: 5mg
Form: Supplied as a white solid.
Purity: ~98% (HPLC)

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