Home  >  Products  >  ABHD4 (abhydrolase domain containing 4, Alpha/beta-hydrolase 4, FLJ12816, Lyso-N-acylphosphatidylethanolamine lipase)
ABHD4 (abhydrolase domain containing 4, Alpha/beta-hydrolase 4, FLJ12816, Lyso-N-acylphosphatidylethanolamine lipase)

ABHD4 (abhydrolase domain containing 4, Alpha/beta-hydrolase 4, FLJ12816, Lyso-N-acylphosphatidylethanolamine lipase)

Cat no: A0004-69A

Supplier: United States Biological
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The protein encoded by this gene belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. It differs from other members of this subfamily in that its putative catalytic triad contains an asparagine instead of the serine residue. Mutations in this gene have been associated with Chanarin-Dorfman syndrome, a triglyceride storage disease with impaired long-chain fatty acid oxidation. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:16000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: A0004-69A
Reactivities: Human, Mouse, Rat, Canine
Hosts: Goat
Applications: ELISA
Size: 100ug
Form: Supplied as a liquid in 0.5 mg/ml tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type: Pab
Purity: Purified by immunoaffinity chromatography.
References: 1. Simon GM, Cravatt BF. Endocannabinoid biosynthesis proceeding through glycerophospho-N-acyl ethanolamine and a role for alpha/beta-hydrolase 4 in this pathway. J Biol Chem. 2006 Sep 8;281(36):26465-72. Epub 2006 Jul 3.
Additional info: Recognizes human ABHD4. Species Crossreactivity: Dog, mouse and rat.

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