Home  >  Products  >  Acid Phosphatase 1 (ACP1, Adipocyte Acid Phosphotase, HAAP, Low Molecular Weight Cytosolic Acid Phosphatase, Low Molecular Weight Phosphotyrosine Protein Phosphotase, LMW-PTP, LMW-PTPase, Red Cell Acid Phosphotase 1)
Acid Phosphatase 1 (ACP1, Adipocyte Acid Phosphotase, HAAP, Low Molecular Weight Cytosolic Acid Phosphatase, Low Molecular Weight Phosphotyrosine Protein Phosphotase, LMW-PTP, LMW-PTPase, Red Cell Acid Phosphotase 1)

Acid Phosphatase 1 (ACP1, Adipocyte Acid Phosphotase, HAAP, Low Molecular Weight Cytosolic Acid Phosphatase, Low Molecular Weight Phosphotyrosine Protein Phosphotase, LMW-PTP, LMW-PTPase, Red Cell Acid Phosphotase 1)

Cat no: A0560-19D

Supplier: United States Biological
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ACP1 (E.C 3.1.3.2) is a unique member of Phosphotyrosine Protein phosphotase family of proteins. It is ubiquitously expressed acid phosphotase functioning as an acid phosphotase and a protein tyrosine phosphotase. ACP1 has a cysteine-based catalytic mechanism and hydrolyzes protein tyrosine phosphate to protein tyrosine and orthophosphate. Reports suggest a functional role of ACP1 in TCR signaling and control of cell-cell adhesion through regulation of cytoskeletion assembly. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1-3ug/ml Optimal dilutions to be determined by the researcher. Positive Control: Liver lysate Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: A0560-19D
Reactivities: Human
Hosts: Rabbit
Applications: Western Blot
Size: 100ug
Form: Supplied as a liquid in PBS, 0.2% gelatin, 0.05% sodium azide.
P type: Pab
Isotype: IgG
Purity: Purified by Protein G affinity chromatography.
Alternative names: EC=3.1.3.48, EC=3.1.3.2, MGC3499, MGC111030
References: 1. Wo,Y.Y., McCormack,A.L., Shabanowitz,J., Hunt,D.F., Davis,J.P., Mitchell,G.L. and Van Etten,R.L. Sequencing, cloning, and expression of human red cell-type acid phosphatase, a cytoplasmic phosphotyrosyl protein phosphatase J. Biol. Chem. 267 (15), 10856-10865 (1992) 2. Bottini et.al 277 (27), 24220-24224 (July 5, 2002) 3. Giannoni et.al JBC 278 (38), 36763-36776 (September 19, 2003).
Additional info: Recognizes human Acid phosphatase 1 (ACP1). Species sequence homology: chicken, canine, mouse, orangutan, rat.

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