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Acin1a, ID (Acin1a Protein, Acin1-a)

Cat no: A0599-97


Supplier: United States Biological
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Apoptotic chromatin condenser inducer 1a (acin-1a) is a zebrafish gene similar to the human gene Acinus. However, there is little published scientific literature currently available for zebrafish acin-1a. Human Acinus is a nuclear factor involved in the induction of apoptotic chromatin condensation after cleavage by caspase-3. One study demonstrated AAC-11, a survival protein that prevents growth factor deprivation initiated apoptosis, binds Acinus to prevent Acinus-mediated DNA fragmentation. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:5000-1:20,000 Western Blot: 1:500-1:1000 Optimal dilutions to be determined by the researcher. Control Peptide: A0599-97P Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: A0599-97
Reactivities: Zebrafish/Fish
Hosts: Rabbit
Applications: ELISA, Western Blot
Size: 250ul
Form: Supplied as a liquid in 40mM MOPS, pH 7.5, 0.1% BSA, 0.1% sodium azide, 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by immunoaffinity chromatography.
References: 1. http://www.uniprot.org/uniprot/B0R0I0. 2. Sahara, S et al (1999) Nature 401:168-173. 3. Rigou, P et al (2009) EMBO J. 28:1576-1588.
Additional info: Recognizes zebrafish Acin-1a.

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