Home  >  Products  >  ACTH, NT (Adrenocorticotropic Hormone, Adrenocorticotropin, Corticotropin)
ACTH, NT (Adrenocorticotropic Hormone, Adrenocorticotropin, Corticotropin)

ACTH, NT (Adrenocorticotropic Hormone, Adrenocorticotropin, Corticotropin)

Cat no: A0758-01E

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
ACTH which, as a synthetic analogue of naturally-occurring Adrenocorticotropic Hormone, can be used to measure adrenal reserve and for the diagnosis of adrenal insufficiency by acute adrenocortical stimulation. ACTH, released from the anterior pituitary gland in response to corticotropin-releasing hormone from the hypothalamus, acts on the adrenal cortex to stimulate the production of corticosteroids such as cortisol, involved in the response to stress. Studies have shown that the administration of 1-24 ACTH increases blood pressure, believed to be attributed to an increase in ACTH-stimulated cortisol secretion, in association with increased cardiac output. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 1:100-1:200 Requires protein digestion pre-treatment of paraffin sections e.g. trypsin or pronase. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: A0758-01E
Hosts: Mouse
Applications: ELISA, Immunohistochemistry
Size: 1mg
Form: Supplied as a liquid in PBS, 0.09% sodium azide.
P type: Mab
Isotype: IgG1
Purity: Purified
Alternative names: Beta-endorphin, Corticotropin-like Intermediary Peptide, CLIP, Lipotropin beta, Beta-LPH, Lipotropin gamma, Gamma-LPH, Melanotropin alpha, Alpha-MSH, Melanotropin beta, Beta-MSH, Melanotropin gamma, Gamma-MSH, Met-enkephalin, Potential Peptide
References: 1. Hatakeyama, H. et al. (2000) Functional adrenocorticotropic hormone receptor in cultured human vascular endothelial cells. Possible role in control of blood pressure. Hypertens. 36:862-865.
Additional info: Recognizes human ACTH (aa1-24). Does not recognise ACTH (aa17-39). Species Crossreactivity: rat

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave