Innoprot HiTSeeker ADRB2 Cell Line has been designed to assay compounds or analyze their capability to modulate Adrenergic beta-2 Receptor. When an agonist binds to the ADRB2 a G protein is activated, which in turn, triggers a cellular response mediated by second messengers (cAMP). This cell line has been validated measuring cAMP increase in the cytosol. The high reproducibility of this assay allows monitoring ADRB2 receptor activation process in High Throughput Screening.
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