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ATF-2 (phospho Ser62) Polyclonal Antibody

Cat no: ABP50267


Supplier: Abbkine Scientific Co.Ltd.
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ATF2 encodes a transcription factor(activating transcription factor 2) that is a member of the leucine zipper family of DNA binding proteins. Activating transcription factor 2 has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Activating transcription factor 2 binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Activating transcription factor 2 may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this ATF2.
Catalogue number: ABP50267
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: ELISA, Immunohistochemistry - fixed, Immunoprecipitation, Western Blot
Size: 30micro l, 100micro l, 200micro l
Accession: P15336
Gene: 1386
Concentration: 1 mg/ml
Isotype: Rabbit IgG
Clonality: Polyclonal

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