A potent (Ki=0.6nM), specific and reversible proteasome inhibitor. It inhibits cell proliferation of H460 cells (Human non-small cell lung cancer cell lines) with an IC50 of 0.1uM.
DMSO (200mg/ml) or EtOH (200mg/ml)
Supplied as a white to off-white solid.
1. Ling, Y., et al. (2003). Clin.Cancer Res. 9, 1145-1154. 2. Adams, J. (2002). The Oncologist 7, 9-16.
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