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CD205 (K499) Peptide

CD205 (K499) Peptide

Cat no: BS9211P


Supplier: Bioworld Technology, Inc.
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DEC-205 (LY75, lymphocyte antigen 75, GP200-MR6) is a 1,695 residue (mature form) multilectin receptor that belongs to the MMR (macrophage mannose receptor) family of multidomain molecules. MMR family molecules mediate membrane receptor targeting to endosomes or lysosomes rich in major histocompatibility complex class II (MHC II) products. Expressed in mature dendritic cells (DC), DEC-205 contains an extracellular N-terminal cysteine-rich domain, a fibronectin type II domain, ten C-type carbohydrate recognition domains, a single transmembrane region and a small cytoplasmic C-terminal domain (31 amino acids) containing a tyrosine at 1679. DEC-205 elicits either an agonistic or antagonistic effect on IL-4 function, which is demonstrated by the ability of DEC-205 to imitate IL-4-induced maturation of epithelium or to inhibit IL-4-induced proliferation of T cells, respectively.
Catalogue number: BS9211P
Applications: Block/Neutralize/Inhibit
Swiss prot: O60449
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide CD205 (K499). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: CD 205; CD205; CD205 antigen; CLEC 13B; CLEC13B; DEC 205; DEC-205; DEC205; gp200; gp200 MR6; gp200-MR6; LY 75; Ly-75; LY75;
Additional info: This peptide can be used with studies using BS9211 CD205 (K499) pAb.

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