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CD272 (W153) Peptide

CD272 (W153) Peptide

Cat no: BS9212P

Supplier: Bioworld Technology, Inc.
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B and T lymphocyte attenuator (BTLA,CD272) is an immunoglobulin domain-containing glycoprotein whose expression is induced during T cell activation. BTLA is similar to CTLA-4 and PD-1, all of which are co-inhibitory receptors belonging to the CD28 family. However, unlike CTLA-4 and PD-1, BTLA does not interact with B7-Ig family counter receptors. Rather, the herpesvirus entry mediator (HVEM), a TNF receptor, acts as a molecular switch that modulates T cell activation by propagating inhibitory signals through BTLA. The BTLA-HVEM interaction is conserved between mouse and human, suggesting that this system is an important pathway regulating lymphocyte activation.
Catalogue number: BS9212P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q7Z6A9
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide CD272 (W153). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: BTLA; BTLA; BTLA1; CD272; CD272 antigen; FLJ16065; MGC129743;
Additional info: This peptide can be used with studies using BS9212 CD272 (W153) pAb.

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