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CD37 Monoclonal Antibody (Clone IPO-24)

CD37 Monoclonal Antibody (Clone IPO-24)

Cat no: 10004718


Supplier: Cayman Chemical Company
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Host: mouse, clone IPO-24 . Cross Reactivity: (+) human CD37 . Application(s): (+) FC, ICC, and IHC (formalin-fixed paraffin-embedded tissue and frozen sections); (-) WB
Catalogue number: 10004718
Hosts: Mouse
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot
Weight: 0
Form: 1 ea
P type: Antibodies
Shipping temp: 4
Storage temp: 4
Additional info: CD37 is a type III transmembrane glycoprotein (Mr = 40-52 kDa). The leukocyte-specific protein CD37 is a member of the tetraspanin superfamily, originally described as a cell surface glycoprotein expressed on mature human B cells, but not on pro-B cells or plasma cells. T cells and monocytes express CD37 at low levels. In humans, CD37 expression is restricted to B and T lymphocytes, monocytes, macrophages, neutrophils, dendritic cells, and certain leukocyte-derived malignant cells. CD37 is not expressed by NK cells, platelets, or erythrocytes. CD37 monoclonal antibody is recommended for immunophenotyping of B cell neoplasia (B cell chronic lymphocytic leukemia, hairy cell leukemia, and B cell non-Hodgkin's lymphomas). Human, rat, and murine CD37 sequences have been identified.

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