Cefsulodin.Sodium Salt is a third generation cephalosporin antibiotic. Utilized in microbiology within CIN agar, which is a yersinia selective agar. The Cefsulodin-Cefzilare are a class of beta-lactam antibiotics. Together with cephamycins, they constitute a subgroup of beta-lactam antibiotics called cephems. Cefsulodin are bactericidal and have the same mode of action as other beta-lactam antibiotics. Cefsulodin-Cefzil disrupt the synthesis of the peptidoglycan layer of bacterial cell walls. The peptidoglycan layer is important for cell wall structural integrity. Cephalosporin compounds were first isolated from cultures of Cephalosporium acremonium from a sewer in Sardinia in 1948 by Italian scientist Giuseppe Brotzu.
Systematic (IUPAC) Name:
4-(aminocarbonyl)-1-[((6R,7R)-2-carboxy-8-oxo-7-{[phenyl(sulfo)acetyl]amino}-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl)methyl]pyridinium
Potency (Anhydrous): (same/more than)85%
Solubility:
Colorless, clear, complete
pH:
3.3-4.8
Water Content:
(same/less than)5%
Absorbance:
250-280nm
Specific Rottion: +16.5-20.0
Arsenic:
(same/less than)0.0002%
Heavy Metals:
(same/less than)0.002%
Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Protect from light.
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