A natural metabolite produced by genus Chaetomium. Acts as an inhibitor of HIF-1 formation by disrupting the binding of p300 to both HIF-1a and HIF-2a. Histone H3K9 methyltransferases G9a and Suv39h inhibitor. Also acts as an immunosuppressant.
Solubility:
DMSO
Molecular Weight:
~710.87
Storage and Stability:
Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
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