Chloride is the anionic form of chlorine. It is the most common of the anions found in living organisms. Chloride ions play a variety of important physiological roles. Chloride channels are found in a variety of cells and are responsible for setting resting cell membrane potential and regulating cell volume. In the nervous system, the action of glycine and GABA are related to chloride levels in specific neurons. Chloride is also instrumental in maintaining the acid-base balance in blood. The kidneys are instrumental in closely regulating serum chloride levels. There are a number of pathologies associated with defective chloride transport; the most well-known being Cystic Fibrosis, caused by a mutation in CFTR a membrane chloride transporter.
Sample Type:
Cell and tissue culture supernatants, urine, plasma and serum, as well as many other biological fluids.
Intended Use:
The assay is linear in the range 20-120 nmol Chloride/well with detection sensitivity ~0.4mM chloride.?
Test Principle:
Chloride BioAssay(TM) Kit provides a quick, simple method for quantification of Chloride in a variety of biological samples. Blood and urine can be used directly after dilution with water. The assay is based upon the competition of Hg
Quick Search
Products 
