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Products Cytokeratin Monoclonal Antibody (Clone C-11)
| Catalogue number: | 10004600 |
| Hosts: | Mouse |
| Applications: | Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Western Blot |
| Weight: | 0 |
| Form: | 1 ea |
| P type: | Antibodies |
| Shipping temp: | 4 |
| Storage temp: | 4 |
| Additional info: | This pan-cytokeratin antibody detects cytokeratin isoforms 4, 5, 6, 8, 10, 13, and 18. Cytokeratins make up a large family of proteins classifed as intermediate filament polypeptides. They are subdivided into type I (acidic) and type II (basic/neutral) proteins. Under normal conditions, these proteins are found in epithelial cells as type I/type II pairs. These pairs provide cellular support as well as contributing to more dynamic processes. They undergo extensive post translational modifications, such as phosphorylation, and are important for cancer diagnostics. This antibody recognizes human cytokeratins 4, 5, 6, 8, 10, 13, and 18. Accordingly the molecular migration is isoform dependent and expected to range from 40 to 70 kDa depending upon the cytokeratin composition of the sample. |
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