Home  >  Products  >  Darunavir ([(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenyl-methyl)propyl]carabamic Acid (3R,3aS,6aR)-Hexahydrofuro[2,3-b]-furan-3-yl Ester, TMC-114, UIC-94017)
Darunavir ([(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenyl-methyl)propyl]carabamic Acid (3R,3aS,6aR)-Hexahydrofuro[2,3-b]-furan-3-yl Ester, TMC-114, UIC-94017)

Darunavir ([(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenyl-methyl)propyl]carabamic Acid (3R,3aS,6aR)-Hexahydrofuro[2,3-b]-furan-3-yl Ester, TMC-114, UIC-94017)

Cat no: D1078

Supplier: United States Biological
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Second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral. Melting Point: 130-132 degrees C Solubility: Chloroform, Methanol Method for Determining Identity: Proton NMR (CDCl3) Spectroscopic Analysis TLC Conditions: SiO2: Dichloromethane: Methanol; 10:1; Visualized with UV and AMCS; Single spot; Rf=0.55. Ethanol Content: 6.5% Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20 degrees C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. Toxicity and Hazards:
Catalogue number: D1078
Size: 5mg
Form: Supplied as an off-white to pale beige solid.
Purity: ~90%
Alternative names: [(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenyl-methyl)propyl]carabamic Acid (3R,3aS,6aR)-Hexahydrofuro[2,3-b]-furan-3-yl Ester; TMC-114; UIC-94017
References: 1. Koh Y., et al. Antimicrob. Agents Chemother. 47, 3123 (2003). 2. Arasteh K., et al. AIDS. 19, 943 (2005). 3. Surleraux, D.L.N.G., et al. J. Med. Chem. 48, 1813 (2005).

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