Dsg1 (I194) Peptide

Cat no: BS9216P

Supplier: Bioworld Technology, Inc.

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Desmogleins (dsgs) are type I membrane proteins that are important for cell adhesion and are expressed in great abundance at the desmosomes, which are adhesive cell junctions. The dsg proteins belong to the cadherin family and consist of dsg1, dsg2 and dsg3. Calcium binds to the putative calcium binding sites at the extracellular N-terminal domain of dsg1, which has cadherin- like repeats. Unlike normal human keratinocytes, the squamous cell carcinoma cells exhibit diminished or unusual expression of dsg3 and dsg1, which bear pemphigus vulgaris and pemphigus foliaceus antigens, respectively. Cultured normal human keratinocytes express dsg1 and dsg3 mRNA, with or without dsg2 mRNA, which indicates that desmoglein isoforms exhibit abnormal expression and may be related to tumor cell kinetics, such as cell invasion and metastasis.

Catalogue number:	BS9216P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	Q02413
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide Dsg1 (I194). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Cadherin family member 4; CDHF4; Desmoglein-1; Desmosomal Glycoprotein 1; DG1; DGI; DSG; DSG1; DSG1; Pemphigus Foliaceus Antigen; PPKS1; SPPK1;
Additional info:	This peptide can be used with studies using BS9216 Dsg1 (I194) pAb.

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Dsg1 (I194) Peptide

Cat no: BS9216P

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