EF-Tu (L338) Peptide

Cat no: BS9146P

Supplier: Bioworld Technology, Inc.

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EF-Ts, also known as TSFM (Ts translation elongation factor, mitochondrial) or COXPD3, is a 325 amino acid protein that is one of 13 mitochondrial-encoded proteins that work together during the elongation phase of protein biosynthesis on the ribosome. Expressed ubiquitously with highest levels present in liver, kidney and skeletal muscle, EF-Ts associates with EF-Tu, a multidomain GTPase with essential functions in translation, and, via this interaction, facilitates the exchange of GDP for GTP, thereby inducing protein elongation. Mutations in the gene encoding EF-Ts are the cause of combined oxidative phosphorylation deficiency type 3 (COXPD3), a condition characterized by defects in the mitochondrial oxidative phosphorylation system and often characterized by severe metabolic acidosis with encephalomyopathy or with hypertrophic cardiomyopathy. Multiple isoforms of EF-Ts exist due to alternative splicing events.

Catalogue number:	BS9146P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P49411
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide EF-Tu (L338). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Elongation factor Tu, mitochondrial; EFTu; P43; TUFM
Additional info:	This peptide can be used with studies using BS9146 EF-Tu (L338) pAb.

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EF-Tu (L338) Peptide

Cat no: BS9146P

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