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Products Fluprostenol EIA Kit
| Catalogue number: | 516761 |
| Weight: | 0 |
| Form: | 96 Well |
| P type: | Assay Kits|Prostaglandins|Eicosanoids |
| Shipping temp: | -20 |
| Storage temp: | -20 |
| Additional info: | Fluprostenol is a metabolically stable analog of PGF2.alpha. with potent FP receptor agonist activity. The isopropyl ester of fluprostenol has recently been approved for use as an ocular hypotensive drug for the treatment of glaucoma and is sold under the Alcon trade name Travoprost. Acting as a prodrug, Fluprostenol isopropyl ester is converted by esterase activity in the cornea to yield the corresponding active free acid, (+)-fluprostenol. Fluprostenol is also used in the veterinary field for the induction of estrus in livestock. Cayman's Fluprostenol EIA is a sensitive detection method for measuring the free acid form of fluprostenol. The assay also detects the isopropyl ester form of fluprostenol, but with less sensitivity. Samples containing a mixture of the isopropyl ester and free acid should be purified and the compounds separated prior to analysis. The assay has been validated for use in aqueous humor samples. |
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