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Fumitremorgin C

Cat no: F9510


Supplier: United States Biological
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Fumitremorgin C is a tremorgenic mycotoxin isolated from Aspergillus fumigatus. Recent research has recognized Fumitremorgin C as a potent and specific inhibitor of the breast cancer resistance protein (BCRP/ABCG2) multidrug transporter. It reverses multidrug resistance mediated by BCRP and increases cytotoxicity of several anticancer agents in vitro. Solubility: Soluble in ethanol, methanol, DMF or DMSO. Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with ethanol, methanol, DMF or DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Reconstituted product is stable for 6 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: F9510
Size: 250ug
Form: Supplied as an off-white lyophilized powder.
Purity: (same/more than) 95% by HPLC
References: 1. Allen, J.D., et al., Mol. Cancer Ther. 1: 417 (2002). 2. Rabindran, S.K., et al., Cancer Res. 60: 47 (2000). 3. Cui, C.B., et al., J. Antibiot. 49: 527 (1996). 4. Cole, R.J., et al., J. Agric. Food Chem. 25: 826 (1977).

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