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Geldanamycin

Cat no: G2024-51A


Supplier: United States Biological
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Geldanamycin binds specifically to heat shock protein HSP90; inhibits protein maturation. Solubility: Soluble in DMSO at 100mg/ml. Poorly soluble in methanol, ethanol and water; Not recommended for stock solutions. Maximum water solubility is ~20-50uM. Melting Point: 261-266.5C Elemental Analysis: Calculated C: 60.19% H: 7.32% N: 4.84 Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20 degrees C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Catalogue number: G2024-51A
Size: 250mg
Form: Supplied as a yellow powder.
Purity: HPLC, TLC: ~99%
References: 1. Whitesell, L. and Cook, P. "Stable and specific binding of heat shock protein 90 by geldanamycin disrupts glucocorticoid receptor function in intact cells." Mol. Endocr. 10:705-712 (1996).

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