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GSK-3 Inhibitor, AR-A014418, (N-[(4-Methoxyphenyl)methyl]-N

Cat no: 167848


Supplier: United States Biological
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Cell-permeable. A selective glycogen synthase kinase 3 (GSK-3) inhibitor (IC50 = 104nm). Inhibition is competitive with respect to ATP (Ki = 38nm). Exhibits specificity for GSK-3 over cdk2 and cdk5 (IC50 values are > 100 =um) and over 26 other kinases. Inhibits b-amyloid-mediated neurodegeneration in hippocampal slices. Molecular Formula: C??H??N?O?S Solubility: DMSO (~30mg/ml) Molecular Weight: ~308.31D Storage and Stability: May be stored at RT for short-term only. Long-term storage is recommended at -20 degrees C. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Catalogue number: 167848
Size: 2mg
Form: Supplied as an off white solid.
Purity: >98% (TLC)

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