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HC-II (D68) Peptide

HC-II (D68) Peptide

Cat no: BS9125P


Supplier: Bioworld Technology, Inc.
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Heparin cofactor II (HCII) is a glycoprotein in human plasma which rapidly inactivates Thrombin in the presence of dermatan sulfate. Inhibition occurs by formation of a stable equimolar complex between HCII and Thrombin. Certain clinical conditions, such as hepatic failure, disseminated intravascular coagulation, thalasemina and sickle cell anemia, display reduced levels of HCII. However, during pregnancy, physiological levels of HCII expression are elevated. HCII may regulate coagulation and may participate in processes such as inflammation, atherosclerosis and wound repair. HCII is widely distributed among vertebrates and may have a common function in birds, amphibians and mammals.
Catalogue number: BS9125P
Applications: Block/Neutralize/Inhibit
Swiss prot: P05546
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide HC-II (D68). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: HC II; HCF II deficiency; HCF2; Heparin cofactor II precursor; HLS2; Leuserpin 2; LS2; Protease inhibitor leuserpin 2; SERPIND1;
Additional info: This peptide can be used with studies using BS9125 HC-II (D68) pAb.

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