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HDAC5 (phospho Ser498) Polyclonal Antibody

Cat no: ABP50325


Supplier: Abbkine Scientific Co.Ltd.
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Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 5 encoded by HDAC5 belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. HDAC5 is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for HDAC5.
Catalogue number: ABP50325
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: ELISA, Immunofluorescence, Immunohistochemistry - fixed, Western Blot
Size: 30micro l, 100micro l, 200micro l
Accession: Q9UQL6
Gene: 10014
Concentration: 1 mg/ml
Isotype: Rabbit IgG
Clonality: Polyclonal

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