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Human Anti-insulin receptor antibody (AIRA) ELISA Kit

Human Anti-insulin receptor antibody (AIRA) ELISA Kit

Cat no: KTE62466

Supplier: Abbkine Scientific Co.Ltd.
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In molecular biology, the insulin receptor is a transmembrane receptor that is activated by insulin. It belongs to the large class of tyrosine kinase receptors. Two alpha subunits and two beta subunits make up the insulin receptor. The beta subunits pass through the cellular membrane and are linked by disulfide bonds. The alpha and beta subunits are encoded by a single gene (INSR). The insulin receptor has also recently been designated CD220 .The main activity of activation of the insulin receptor is inducing glucose uptake. For this reason "insulin insensitivity", or a decrease in insulin receptor signaling, leads to diabetes mellitus type 2 - the cells are unable to take up glucose, and the result is hyperglycemia (an increase in circulating glucose), and all the sequelae which result from diabetes.
Catalogue number: KTE62466
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Additional info: Human Anti-insulin receptor antibody (AIRA) ELISA Kit has high sensitivity and excellent specificity for detection of Human AIRA. No significant cross-reactivity or interference between Human AIRA and analogues was observed.

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