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Human C-Polypeptide (CP) ELISA Kit

Human C-Polypeptide (CP) ELISA Kit

Cat no: KTE62547

Supplier: Abbkine Scientific Co.Ltd.
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The connecting peptide, or C-peptide, is a short 31-amino-acid polypeptide that connects insulin's A-chain to its B-chain in the proinsulin molecule. In diabetes and other diseases a measurement of C-peptide blood serum levels can be used to distinguish between certain diseases with similar clinical features. In the insulin synthesis pathway, first preproinsulin is translocated into the endoplasmic reticulum of beta cells of the pancreas with an A-chain, a C-peptide, a B-chain, and a signal sequence. The signal sequence is cleaved from the N-terminus of the peptide by a signal peptidase, leaving proinsulin. After proinsulin is packaged into vesicles in the Golgi apparatus (beta-granules), the C-peptide is removed, leaving the A-chain B-chain, bound together by disulfide bonds, that constitute the insulin molecule.
Catalogue number: KTE62547
Reactivities: Human
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Additional info: Human C-Polypeptide (CP) ELISA Kit has high sensitivity and excellent specificity for detection of Human CP. No significant cross-reactivity or interference between Human CP and analogues was observed.

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