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HUNK (T287) Peptide

HUNK (T287) Peptide

Cat no: BS9187P

Supplier: Bioworld Technology, Inc.
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The HUNK (hormonally upregulated Neu-associated kinase) protein, also designated MAK-V in mouse, has been identified as a novel SNF1-related serine/threonine kinase. The human HUNK gene localizes to chromosome 21q22 and encodes a protein with nucleocytoplasmic distribution and localizes to the centrosome. Overexpression of the HUNK protein associates with approximately 50% of breast carcinomas, and may provide diagnostic-prognostic value as a molecular marker. Serine/threonine-protein kinase SNF1-like kinase 2 (SIK) phosphorylates Ser 794 of IRS1 in insulin-stimulated adipocytes, which may modulate the efficiency of insulin signal transduction. SIK is activated by phosphorylation on Thr 175 by STK11 in complex with STE20-related adapter-alpha and CAB39.
Catalogue number: BS9187P
Applications: Block/Neutralize/Inhibit
Swiss prot: P57058
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide HUNK (T287). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: HUNK; HUNK; MAKV;
Additional info: This peptide can be used with studies using BS9187 HUNK (T287) pAb.

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