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IFI16 Antibody

IFI16 Antibody

Cat no: 200210


Supplier: ABBIOTEC
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Interferon-gamma inducible protein 16 (IFI16) belongs to the HIN-200 family of transcriptional regulator linked to cell cycle regulation and differentiation by modulating the activities of multiple transcriptional factors, such as p53 and Rb. The HIN-200 (hematopoeitic interferon-inducible nuclear antigens with 200 amino acid repeat) family members contain a DNA binding domain, a transcriptional regulatory domain, DAPIN/PAAD domain associated with interferon response and a binding domain for BRCA1. IFI16 may have a role in the regulation of hematopoeitic cell differentiation and also be involved in DNA repair since it becomes a component of the DNA repair multi-protein BASC comple, Xenopus/Amphibian, after UV-induced DNA damage. IFI16 is strongly induced by gamma interferon in vivo.
Catalogue number: 200210
Reactivities: Human
Applications: Western Blot
Size: 0.1 mg
Accession: Q16666
Antigen: Recombinant protein encompassing the PAAD domain (aa 6-102) of human IFI16.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
P type: Rabbit Polyclonal Antibody
Isotype: Rabbit Ig
Clonality: ABT-1206
Additional info: Gamma-interferon-inducible protein Ifi-16; Interferon-inducible myeloid differentiation transcriptional activator; IFI16; IFNGIP1
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