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Integrin alpha6 (LC) Peptide

Integrin alpha6 (LC) Peptide

Cat no: BS7036P


Supplier: Bioworld Technology, Inc.
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Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.
Catalogue number: BS7036P
Applications: Block/Neutralize/Inhibit
Swiss prot: P23229
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Integrin alpha6 (LC). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Integrin alpha-6; CD49 antigen-like family member F; VLA-6; CD49f; Integrin alpha-6 light chain; ITGA6
Additional info: This peptide can be used with studies using BS7036 Integrin alpha6 (LC) pAb.

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