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JIK (H571) Peptide

JIK (H571) Peptide

Cat no: BS9257P


Supplier: Bioworld Technology, Inc.
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JNK/SAPK-inhibitory kinase (JIK) is a serine/threonine kinase that belongs to the STE20 kinase family. The kinase domain of JIK is similar to the GCK-like subfamily of STE20 kinases, while its non-catalytic domain is similar to a Caenorhabditis elegans putative serine/threonine kinase, SULU. JIK inhibits c-Jun NH2-terminal kinase/stress-activated protein kinase (JNK/SAPK), which is activated by many types of cellular stresses and extracellular signals. JNK/SAPK regulates cell survival, apoptosis and proliferation in mouse development. JIK is negatively regulated by epidermal growth factor (EGF) and tyrosine kinase receptors. In unstimulated human T cells, JIK is cytoplasmic, whereas in the continuously dividing human T cells of Jurkat lymphoma, JIK is nuclear.
Catalogue number: BS9257P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q9H2K8
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide JIK (H571). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: KDS; MAP3K18; TAO kinase 3; TAOK3; DPK; FLJ31808; hKFC A; hKFC-A;
Additional info: This peptide can be used with studies using BS9257 JIK (H571) pAb.

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