Home  >  Products  >  Lithocholic acid (3alpha-Hydroxy-5beta-cholan-24-oic acid, 3alpha-Hydroxy-5beta-cholanic acid, 5beta-Cholan-24-oic acid-3alpha-ol, LCA)
Lithocholic acid (3alpha-Hydroxy-5beta-cholan-24-oic acid, 3alpha-Hydroxy-5beta-cholanic acid, 5beta-Cholan-24-oic acid-3alpha-ol, LCA)

Lithocholic acid (3alpha-Hydroxy-5beta-cholan-24-oic acid, 3alpha-Hydroxy-5beta-cholanic acid, 5beta-Cholan-24-oic acid-3alpha-ol, LCA)

Cat no: 167902

Supplier: United States Biological
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Lithocholic acid (LCA) is a hydrophobic secondary bile acid that acts as a detergent to solubilize fats for absorption. Known to display both carcinogenic and apoptotic activities. Also binds to the p53 binding sites of both MDM2 and MDM4 with a five-fold preference for MDM4. Solubility: DMSO, EtOH Molecular Weight: ~376.57 Storage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile buffer or dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: 167902
Size: 1g
Form: Supplied as a white to off-white solid.
Purity: ~97% (TLC)
References: 1. Vogel, S.M., et al. (2012). Proc. Natl. Acad. Sci. USA 109:16906-16910

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