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Products MEK1 (Phospho-Thr292) Polyclonal Antibody
| Catalogue number: | 10009518 |
| Hosts: | Rabbit |
| Applications: | Western Blot |
| Weight: | 0 |
| Form: | 1 ea |
| Antigen: | phosphopeptide corresponding to amino acid residues surrounding the Phospho-Thr292 of human MEK1 |
| P type: | Antibodies|Intracellular Signaling |
| Shipping temp: | -20 |
| Storage temp: | -20 |
| Additional info: | MAP kinase kinase 1 (MAPKK1) is an integral component of the MAP kinase cascade that regulates cell growth and differentiation . This pathway also plays a key role in synaptic plasticity in the brain . Activated MEK1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase . Conversely, there also appears to be a feedback phosphorylation of MEK1 by MAP kinase. The sites on MEK1 that are phosphorylated by MAP kinase on Thr292 and Thr386 . |
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