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MIF (R74) Peptide

MIF (R74) Peptide

Cat no: BS9032P

Supplier: Bioworld Technology, Inc.
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Macrophage migration inhibitory factor, known as MIF or glycosylation-inhibiting factor, is a secreted, homotrimeric, pro-inflammatory cytokine that modulates macrophage and T cell function and is an important regulator of host response to infection. MIF is expressed at sites of inflammation, which suggests that it plays a role in regulating macrophage function in host defense. MIF is produced by the pituitary gland and is found in monocytes, macrophages, differentiating immunological cells in the eye lens and brain, and fibroblasts. Elevated levels of MIF protein are detected in the plasma of patients with severe sepsis or septic shock, a condition where MIF influences endotoxic shock by enhancing the production of other inflammatory cytokines including tumor necrosis factor alpha (TNFalpha), interleukin-1 (IL-1) and interferon-gamma (IFN-gamma ). MIF promotes the systemic inflammatory response by counter-regulating glucocorticoid-mediated inhibition of immune-cell activation and proinflammatory cytokine production. MIF may mediate tissue destruction through the induction of proteinases.
Catalogue number: BS9032P
Applications: Block/Neutralize/Inhibit
Swiss prot: P14174
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide MIF (R74). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: GIF; GLIF; Glycosylation inhibiting factor; Glycosylation-inhibiting factor; L-dopachrome isomerase; L-dopachrome tautomerase; Macrophage migration inhibitory factor; Macrophage migration inhibitory factor; MIF; MIF; MIF protein; MIF; MMIF; Phenylpyruvate tautomerase; Phenylpyruvate tautomerase;
Additional info: This peptide can be used with studies using BS9032 MIF (R74) pAb.

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