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Mouse Anti-Type II Collagen IgG Assay Kit (mouse)

Mouse Anti-Type II Collagen IgG Assay Kit (mouse)

Cat no: 500470


Supplier: Cayman Chemical Company
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Collagen-induced arthritis (CIA) is an experimental autoimmune disease that is widely used as a model of human rheumatoid arthritis (RA) in the study of the pathogenic mechanisms of this disease and for testing potential therapeutics. Circulating levels of anti-type II collagen antibody are strongly associated with the development of arthritis and can be used as a biomarker of CIA. Cayman's Mouse Anti-Type II Collagen IgG Assay (Quantitative, mouse) is an immunometric (i.e., sandwich) assay which can be used to measure anti-type II collagen antibody in plasma or serum without prior sample purification. This kit uses a mouse collagen-coated plate and an affinity-purified polyclonal antibody isolated from mice with CIA is used as a standard. This standard provides the most accurate measurement of anti-CII concentration in experimental samples. One unit of standard in this assay is approximately equal to 1 ng of IgG protein. The standard curve spans the range of 15.6-1,000 U/ml, with an LLOQ of 15.6 U/ml.
Catalogue number: 500470
Weight: 0
Form: 96 Well
P type: Assay Kits
Shipping temp: 4
Storage temp: 4
Additional info: Collagen-induced arthritis (CIA) is an experimental autoimmune disease that is widely used as a model of human rheumatoid arthritis (RA) in the study of the pathogenic mechanisms of this disease and for testing potential therapeutics. Circulating levels of anti-type II collagen antibody are strongly associated with the development of arthritis and can be used as a biomarker of CIA. Cayman's Mouse Anti-Type II Collagen IgG Assay (Quantitative, mouse) is an immunometric (i.e., sandwich) assay which can be used to measure anti-type II collagen antibody in plasma or serum without prior sample purification. This kit uses a mouse collagen-coated plate and an affinity-purified polyclonal antibody isolated from mice with CIA is used as a standard. This standard provides the most accurate measurement of anti-CII concentration in experimental samples. One unit of standard in this assay is approximately equal to 1 ng of IgG protein. The standard curve spans the range of 15.6-1,000 U/ml, with an LLOQ of 15.6 U/ml.

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