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Mouse TM2 domain-containing protein 1 (TM2D1) ELISA Kit

Cat no: KTE70206


Supplier: Abbkine Scientific Co.Ltd.
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TM2D1 is a beta-amyloid peptide-binding protein. It contains a structural module related to that of the seven transmembrane domain G protein-coupled receptor superfamily and known to be important in heterotrimeric G protein activation. Beta-amyloid peptide has been established to be a causative factor in neuron death and the consequent diminution of cognitive abilities observed in Alzheimer's disease. This protein may be a target of neurotoxic beta-amyloid peptide, and may mediate cellular vulnerability to beta-amyloid peptide toxicity through a G protein-regulated program of cell death.BBP bound the 42-amino acid form of human beta-amyloid peptide in vitro with high affinity and specificity. Expression of a signaling-deficient dominant-negative BBP mutant suppressed sensitivity of human Ntera-2 neurons to beta-amyloid-mediated toxicity.
Catalogue number: KTE70206
Reactivities: Mouse
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q99MB3
Gene: 94043
Additional info: Mouse TM2 domain-containing protein 1 (TM2D1) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse TM2D1. No significant cross-reactivity or interference between Mouse TM2D1 and analogues was observed.

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