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Mouse Transmembrane protein 55B (TMEM55B) ELISA Kit

Cat no: KTE70176


Supplier: Abbkine Scientific Co.Ltd.
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TMEM55B catalyzes the degradation of phosphatidylinositol 4,5-bisphosphate (PtdIns-4,5-P2) by removing the 4-phosphate. The deduced 257-amino acid protein contains a central Cx(5)R phosphatase catalytic motif and 2 transmembrane domains near its C terminus, a characteristic of lysosomal transmembrane proteins. RNA dot blot analysis detected expression in all tissues examined. Fluorescence-tagged TMEM55B localized with membrane markers of late endosomes or lysosomes. Endogenous HeLa cell TMEM55B showed a similar distribution.It showed no activity toward other phosphatidylinositol substrates or inositol phosphates tested. Overexpression of TMEM55B in human embryonic kidney cells reduced the total cellular level of PtdIns-4,5-P2.
Catalogue number: KTE70176
Reactivities: Mouse
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q3TWL2
Gene: 219024
Additional info: Mouse Transmembrane protein 55B (TMEM55B) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse TMEM55B. No significant cross-reactivity or interference between Mouse TMEM55B and analogues was observed.

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