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Mouse Transmembrane protein 98 (TMEM98) ELISA Kit

Cat no: KTE70162


Supplier: Abbkine Scientific Co.Ltd.
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The intracellular signaling pathway by which TNF induces its pleiotropic actions is well-characterized and includes unique components, as well as modules shared with other signaling pathways. TMEM9B as an important component of TNF signaling and which is a module shared with the IL-1? and Toll-like receptor (TLR) pathways. is a glycosylated protein localized in membranes of the lysosome and partially in early endosomes. The expression of TMEM9B is required for the production of proinflammatory cytokines induced by TNF, IL-1?, and TLR ligands, but not for apoptotic cell death triggered by TNF or Fas ligand. TMEM9B is essential in TNF activation of both the NF-?B and MAPK pathways.TMEM9B is a key component of inflammatory signaling pathways and suggest that endosomal or lysosomal compartments regulate these pathways.
Catalogue number: KTE70162
Reactivities: Mouse
Applications: ELISA
Size: 48T, 96T, 96T*5, 96T*50
Accession: Q91X86
Gene: 103743
Additional info: Mouse Transmembrane protein 98 (TMEM98) ELISA Kit has high sensitivity and excellent specificity for detection of Mouse TMEM98. No significant cross-reactivity or interference between Mouse TMEM98 and analogues was observed.

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