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MRCKalpha (L663) Peptide

MRCKalpha (L663) Peptide

Cat no: BS9192P


Supplier: Bioworld Technology, Inc.
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Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues. Myotonic dystrophy kinase-related Cdc42-binding (DMPK-like) kinases-a and b (MRCK-a, b) contain a cysteine-rich motif and a putative pleckstrin homology domain. MRCKs can phosphorylate nonmuscle myosin light chain and influences actin-myosin contractility (3,4). MRCK-a can phosphorylate and activate LIM kinases downstream of Cdc42, which leads to inactivation of ADF/cofilin and to Actin cytoskeletal reorganization. MRCK-a can also influence neurite outgrowth promoted by Cdc42 and Rac.
Catalogue number: BS9192P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q5VT25
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide MRCKalpha (L663). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: MRCK alpha; mrck; mrcka; DMPK like; DMPK-like alpha; CDC42 binding protein kinase beta; CDC42-binding protein kinase alpha; CDC42BPA;
Additional info: This peptide can be used with studies using BS9192 MRCKalpha (L663) pAb.

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