Home  >  Products  >  Nav1.1, S74-71
Nav1.1, S74-71

Nav1.1, S74-71

Cat no: SMC-376D


Supplier: StressMarq Biosciences Inc.
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Detects ~220kDa. No cross reactivity against Nav1.2, Nav1.3 and Nav1.6
Catalogue number: SMC-376D
Reactivities: Human, Mouse, Rat
Hosts: Mouse
Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
Size: 100ug
Clone: S74-71
Accession: NP_061203.2
Gene: 20265
Swiss prot: Q62206
Dilutions: 1ug/mL (WB), 0.1-1ug/mL (IHC/ICC), 1-10ug/mL (IF)
Form: Protein G Purified
Storage buffer: PBS pH7.4, 50% glycerol
Concentration: 1mg/mL
Isotype: 1gG1
Shipping temp: Blue Ice or 4
Storage temp: -20
Research area: Ion Channels
Certificate of analysis: 1 ug/mL of SMC-376 was sufficient for detection of Nav1.1 in 20ug of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
Scientific background: Voltage gated sodium channels initiate action potentials in neurons. Nav1.1 is abundant in the adult brain, and primarily localized in cell bodies. Mutations in the Nav1.1 channels cause generalized epilepsy with febrile seizures plus (GEFS+). Studies sho
Alternative names: FEB3, Scn1a, GEFSP2, HBSCI, SCN1
References: 1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA. 2. www.iochannels.org 3. Kalume F., et al. (2007) J Neurosci. 27(41): 11065- 11074.
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave