Home  >  Products  >  p38beta, Active, Recombinant (p38 beta, P38, p38, p38beta, p38b, human P38beta, active kinase, active kinases, recombinant P38beta, recombinant P38b, kinase activity assay, protein kinase)

p38beta, Active, Recombinant (p38 beta, P38, p38, p38beta, p38b, human P38beta, active kinase, active kinases, recombinant P38beta, recombinant P38b, kinase activity assay, protein kinase)

Cat no: 167930


Supplier: United States Biological
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p38-beta is a member of the p38 MAP kinase family and is activated by both proinflammatory cytokines and environmental stress. The p38-beta is activated through its phosphorylation by MAP kinase kinases (MKKs), preferably by MKK6. Transcription factor ATF2/CREB2 has been shown to be a substrate of this kinase. Alternatively spliced transcript variants encoding the same protein have been observed. Source: Recombinant protein corresponding to Active p38 beta expressed in Sf9 insect cells Molecular Weight: ~71.0kD Biological Activity: The specific activity of P38BETA was determined to be 123nmol/min/mg as per activity assay protocol. Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: 167930
Size: 5ug
Form: Supplied as a liquid in 50mM Tris-HCl, pH 7.5,150mM NaCl, 0.25mM DTT, 0.1mM EGTA, 0.1mM EDTA, 0.1mM PMSF, 25% glycerol.
Purity: ~90% (SDS-PAGE)
References: 1.Jiang, Y. et al: Characterization of the structure and function of a new mitogen-activated protein kinase (p38- beta). J. Biol. Chem. 271: 17920-17926, 1996. 2. Stein, B. et al: p38-2, a novel mitogen-activated protein kinase with distinct properties. J. Biol. Chem. 272: 19509- 19517, 1997.

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