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Products Prostaglandin D Synthase (lipocalin-type; mouse) Polyclonal Antibody
| Catalogue number: | 10004344 |
| Hosts: | Rabbit |
| Applications: | Immunohistochemistry, Western Blot |
| Weight: | 0 |
| Form: | 1 ea |
| Antigen: | recombinant mouse L-PGD synthase |
| P type: | Antibodies|Eicosanoids |
| Shipping temp: | -20 |
| Storage temp: | -20 |
| Additional info: | Prostaglandin D synthase (PGDS) catalyzes the isomerization of PGH2 to produce PGD2. PGD2 induces sleep, regulates nociception, inhibits platelet aggregation, and acts as an allergic mediator. Two distinct types of PGDS have been identified, namely the lipocalin type enzyme (.beta.-trace) and the hematopoietic enzyme. Lipocalin-type PGDS (L-PGDS) is localized in the central nervous system, genital organs of various mammals and the human heart. Patients with chronic renal failure and hypertension exhibit elevated amounts of L-PGDS in serum and urine. The L-PGD synthase has been identified as (beta)-trace, which is a major protein in the human cerebrospinal fluid. |
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