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Rabbit Anti-Human p53 (phospho Ser15) monoclonal antibody, clone 25I72M35

Cat no: CABT-L1642


Supplier: Creative Diagnostics
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Rabbit Anti-Human p53 (phospho Ser15) monoclonal antibody for ChIP, FC, FRET, ICC, IF, WB. The p53 tumor suppressor protein plays a major role in cellular response to DNA damage and other genomic aberrations. Activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. p53 acetylation at Lys382 is required for recruitment of p300 to the p21 promoter, and is mediated by p300 and CBP acetyltransferases. Acetylation appears to play a positive role in the accumulation of p53 protein in stress responses, and inhibition of deacetylation stabilizes p53.
Catalogue number: CABT-L1642
Reactivities: Human
Hosts: Rabbit
Applications: ChIP
Conjugates: Unconjugated
Clone: 25I72M35
Target: TP53
Isotype: IgG
Clonality: Monoclonal
Storage temp: Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C

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