Rabbit Anti-Human TIE1 polyclonal antibody

Cat no: CABT-L1868

Supplier: Creative Diagnostics

0 reviews | Write a Review Pencil

Read More on Supplier Website

Description
Additional Information

Rabbit Anti-Human TIE1 polyclonal antibody for IHC-P. TIE-1/TIE (tyrosine kinase with Ig and EGF homology domains 1) and TIE2/Tek define a new class of the receptor tyrosine kinase (RTK) subfamily with unique structural characteristics: two immunoglobulin like domains flanking three epidermal growth factor (EFG) like domains followed by three fibronectin type III like repeats in the extracellular region and a split tyrosine kinase domain in the cytoplasmic region. Human TIE-1 cDNA encodes a 1138 amino acid residue precursor protein with a putative signal peptide, an extracellular domain, and a cytoplasmic domain. TIE-1 and TIE-2, expressed primarily on endothelial and hematopoietic progenitor cells, play important roles in angiogenesis, vasculogenesis, and hematopoiesis. In developing vascular endothelial cells, TIE-1 and TIE-2 are specifically expressed. Two ligands that bind TIE have been identified, angiopoietin 1 and angiopoietin 2. Based on gene targeting studies, the in vivo functions of TIE-1 are related to endothelial cell differentiation.

Catalogue number:	CABT-L1868
Reactivities:	Human
Hosts:	Rabbit
Conjugates:	Unconjugated
Gene:	7075
Target:	TIE1
Isotype:	IgG
Clonality:	Polyclonal
Storage temp:	2-8°C. Do not freeze. The user must validate any other storage conditions. When properly stored, the reagent is stable to the date indicated on the label. Do not use the reagent beyond the expiration date.

See Full Product Listings >

Rabbit Anti-Human TIE1 polyclonal antibody

Cat no: CABT-L1868

Get Quote

About Biosave

Product Categories

Information


Get a Quote Direct from Creative Diagnostics




By submitting this form you agree to your details being passed to Creative Diagnostics for the purpose of generating the best quote*